Un-Complicating Cholesterol and Cardiovascular Disease | Josh Wageman - E407

Aug 11, 2025

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Josh Wageman is a board-certified Clinical Lipid Specialist dedicated to transforming the way we understand and treat heart disease. With a deep expertise in cholesterol, metabolic health, and cardiovascular risk, he helps patients cut through the noise and take control of their health using evidence-based, personalized strategies. Known for translating complex science into actionable steps, Josh is passionate about prevention and proving that heart disease doesn’t have to be inevitable.

In this episode, Dr. Brian and Josh talk about…

(00:00) Intro
(00:32) Josh’s interesting and varied career path
(04:31) Understanding cardiovascular disease in a nutshell
(8:15) Understanding lipoproteins
(10:10) Why lipids are controversial and what we can all agree on
(12:28) LDL and HDL particles
(19:35) Endurance athletes and coronary calcium
(29:54) Atherosclerosis, carnivore, and gut dysbiosis
(39:46) Advanced lipid panels
(40:29) Statins and LDL
(44:13) Pros and cons of statins
(49:54) Supplements that may be helpful for cardiovascular health
(52:44) Rapping and singing about lipids and heart health
(55:09) Science and faith; physical health and spiritual health
(01:02:25) Outro

For more information, please see the links below. Thank you for listening!

Links:

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Josh Wageman:

Dr. Brian Lenzkes:

Website: https://arizonametabolichealth.com/
Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author

Dr. Tro Kalayjian:

Website: https://www.doctortro.com/
Twitter: https://twitter.com/DoctorTro
Instagram: https://www.instagram.com/doctortro/

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