This Week in Cardiology

May 02, 2025 This Week in Cardiology

May 2, 2025
The FDA's recent approval of TAVR for asymptomatic aortic stenosis raises questions about trial biases and the necessity of immediate intervention. Innovative diagnostic tools, including machine learning methods to differentiate tachycardia types, are explored for their potential to enhance cardiac care. Additionally, discussions on the implications of the PRAETORIAN-XL trial highlight concerns around methodologies in device therapy, shedding light on how these factors could alter patient outcomes.
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INSIGHT

FDA Approval of TAVR Controversial

  • The FDA approved TAVR for asymptomatic severe aortic stenosis based mainly on the biased EARLY TAVR trial.
  • The trial mainly showed reduced unplanned hospitalizations without survival benefit, raising concerns about expanding TAVR use.
INSIGHT

Machine Learning Sorts Tachycardia Type

  • Machine learning on PPG signals can distinguish between supraventricular and ventricular tachycardia origins.
  • This opens new possibilities for noninvasive arrhythmia diagnosis using wrist-worn devices in clinical settings.
INSIGHT

Stroke Risk Varies by PFO Status

  • Traditional risk factors strongly contribute to cryptogenic ischemic stroke in young people without PFO.
  • In those with PFO, non-traditional factors like migraine with aura play a larger role, indicating different stroke mechanisms.
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