Sam Miller Science S 864: Understanding PCOS and Metabolism: Energy Expenditure, Insulin Resistance, and Fat Loss
PCOS is often discussed in extremes, but the reality is far more nuanced. Drawing from a large meta-analysis, I walk through what the research actually shows about energy expenditure, metabolic flexibility, and fat loss in women with PCOS. This conversation explores why results can vary so widely, how insulin resistance and metabolic adaptation influence outcomes, and where standard calorie-based models fall short.
Topics discussed:
- PCOS and energy balance
- Metabolic rate variability
- Insulin resistance implications
- Metabolic flexibility challenges
- Brown fat and metabolism
- Dieting and metabolic adaptation
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