
Becker’s Healthcare Podcast Cheng-Kai Kao, MD, FACP, SFHM, Chief Medical Information Officer at UChicago Medicine
Nov 28, 2025
Cheng-Kai Kao, MD, is a practicing hospitalist and the Chief Medical Information Officer at UChicago Medicine, specializing in EHR optimization and clinical AI. He dives into the transformative role of technology in enhancing patient care and workflow efficiency. Kao emphasizes the importance of AI governance to ensure responsible implementation. He shares insights on virtual care design that focuses on minimizing patient burden and calls for policies to keep pace with tech advancements. His vision for the future highlights human-centered approaches that engage both clinicians and patients.
AI Snips
Chapters
Transcript
Episode notes
AI Everywhere Demands Careful Validation
- AI is omnipresent across vendors and offers huge potential but creates vetting challenges for health systems.
- Cheng-Kai Kao urges careful validation and time for generative AI to mature before wide clinical reliance.
Chat UCM Adoption Story
- UChicago Medicine built a HIPAA-compliant ChatGPT called Chat UCM and 150 users signed up in three months.
- Staff use it for drafting denial appeals, patient letters, translations, and other efficiency tasks.
Implement AI Governance Processes
- Establish a standardized innovation intake with AI questionnaires and specialist review before adoption.
- Continue post-implementation monitoring to ensure models perform safely in your patient population.
