Plants of the Gods: Hallucinogens, Healing, Culture and Conservation podcast Plants of the Gods: S7E2. The Ethnobotany of Kratom with Dr. Chris McCurdy
Jun 18, 2025
Christopher McCurdy, a leading expert on kratom and a professor at the University of Florida, discusses the dual nature of this fascinating plant. He reveals its potential to treat opioid withdrawal while acting as both a stimulant and a sedative, depending on dosage. The conversation dives into kratom's traditional uses in Southeast Asia, its cultural significance, and the importance of indigenous knowledge in understanding its benefits. McCurdy also emphasizes the need for further research to ensure safety and efficacy, advocating for collaboration with traditional users in the scientific exploration.
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Kratom's Dual Effects & Traditional Use
- Kratom's leaves act as stimulants at low doses and sedatives at higher doses.
- Traditionally, it helps locals combat fatigue and also serves as an opioid substitute to ease withdrawal.
Kratom Extraction & Pharmacokinetics
- Traditional kratom use involves inefficient extraction methods, reducing overdose risks.
- Concentrated extracts deliver alkaloids faster and stronger, increasing potential adverse effects.
Avoid Purified Kratom Alkaloids
- Avoid purified or semi-synthetic kratom alkaloid products, as they can cause overdoses.
- Prefer whole leaf kratom to reduce risk and because it maintains traditional safety profiles.