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RCEM Learning

April 2025

Apr 8, 2025
Maegan Ladell, a pediatric emergency medicine physician and patient safety researcher, shares her insights on fostering a culture of patient safety. She delves into the complexities of diagnostic errors, emphasizing the influence of hindsight bias in high-stakes decision-making. Ladell critiques traditional error analysis methods and advocates for a systems-thinking approach that considers the interplay of human behavior and healthcare systems. This engaging discussion highlights the necessity for a more nuanced understanding of medical errors to improve patient care in emergency settings.
01:15:32

Episode guests

Podcast summary created with Snipd AI

Quick takeaways

  • The trial on Landiolol indicated that while beta-blockers can effectively control heart rates in septic shock, they did not significantly reduce mortality rates.
  • New guidelines advocate for comprehensive mortality reviews in emergency departments to enhance care quality and identify learning opportunities.

Deep dives

Beta Blockers in Septic Shock

The podcast discusses a trial investigating the use of beta blockers, specifically Landialol, in patients with septic shock and tachycardia. The trial aimed to determine if beta blockers could improve patient outcomes by controlling heart rates above 95 beats per minute, which is linked to increased mortality. The findings indicated that while beta blockers effectively lowered heart rates without increasing vasopressor requirements, there was no significant change in mortality rates between the treated and control groups. The discussion raises critical questions regarding the trial's methodology, including its open-label design and the clinical relevance of its primary composite endpoints.

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