Dr. Lisa Higgins presents long-term outcomes of REMAP-CAP trial at Critical Care Reviews Meeting 2023. Prof. Christopher Seymour explores 180-day outcomes for pandemic patients. Analysis includes treatments like antivirals, corticosteroids, and anticoagulants. Challenges in post-ICU follow-up and successes of platforms like Remap Cap discussed.
REMAP-CAP trial examined long-term outcomes of COVID-19 treatments on ICU patients.
Study showed variations in survivor outcomes with different treatments for COVID-19 patients.
Deep dives
Overview of Remap-Cap Presentation
The Remap-Cap presentation discusses a follow-up paper on pandemic patients from the Remap-Cap trials led by Dr. Lisa Higgins. The trial's design as a platform trial allowed for simultaneous study of various treatments for COVID-19. The focus was on critically ill patients, with randomization to different treatment domains. Results from six domains were published, showing varied outcomes such as benefit, harm, or no effect.
Long-Term Outcomes in Remap-Cap
The analysis explored 180-day outcomes in the Remap-Cap trial for pandemic patients. The trial included over 12,000 patients, with results published for seven domains that studied treatments for COVID-19 patients. Findings revealed the effects of interventions on longer-term mortality, disability, and quality of life. The analysis aimed to understand the impact of various treatments on ICU patients with COVID-19.
Quality of Life and Disability Measures
The study assessed quality of life and disability in ICU survivors at day 180 post-admission. Results indicated that survivors receiving antiplatelets had a higher quality of life, while certain treatments showed no difference in outcomes. The study used measures like EQ5D5L and WHODAS 2.0 to evaluate health-related quality of life and disability categories.
Impact and Reflection on Pandemic Response
The podcast reflects on the global response to the COVID-19 pandemic, highlighting successes and failures. It discusses the scientific achievements in developing treatments like dexamethasone and vaccines within a short timeframe. Moreover, it identifies challenges in public health communication, vaccine distribution, and healthcare inequalities, emphasizing the need for improved preparation and response strategies for future pandemics.
Dr Lisa Higgins (Melbourne) presents the long term outcomes of the REMAP-CAP domains at the Critical Care Reviews Meeting 2023. Prof Howard Bauchner (Boston) delivers an editorial. Prof Christopher Seymour (Pittsburgh) chairs the session.
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