Key points on Lemiere's Disease

Lemiere's disease is a rare life-threatening condition characterized by thrombophlebitis of the internal jugular vein with bacteremia, commonly caused by anaerobic bacteria. It typically presents in young adults and adolescents with symptoms such as fever, pharyngeitis, anterior cervical lymphadenopathy, and neck mass. Diagnosis is often clinical, as lab tests are nonspecific. Treatment involves broad-spectrum antibiotics, typically piptazo for toxic patients and a penicillin plus clinomycin or anpicillin cell back-dam for non-toxic patients. It is essential to consider Lemiere's disease in patients with prolonged pharyngitis, worsened symptoms, neck pain, and signs of metastatic disease.