The Drug Science Podcast 139. Poppers with Adam Zmith
Oct 29, 2025
Adam Zmith, a writer and producer known for his work on queer history and author of "Deep Sniff," dives into the fascinating world of poppers. He examines their complex history and regulation while highlighting their cultural significance within the queer community. Zmith discusses the evolution of poppers from Victorian medical use to their branding in the 1970s nightlife scene. He explores the implications of policing and the need for harm reduction, positioning poppers as a metaphor for queer visibility and resilience. History becomes a lens for envisioning inclusive queer futures.
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How Poppers Work
- Poppers are alkyl nitrites inhaled as vapour that dilate blood vessels and relax muscles.
- The effect is brief, disinhibiting, and can enhance sexual connection and physical relaxation.
Writing Deep Sniff During Lockdown
- Adam wrote the first draft of Deep Sniff during COVID lockdown using online archives and the Wellcome Library.
- He combined archival research with personal reflection and listening to music to shape the book.
From 1844 Discovery To Medical Use
- Amyl nitrite was first isolated in 1844 and later repurposed by Thomas Lauder Brunton for angina treatment.
- Clinicians discovered its vasodilatory effect relieved angina pain quickly, informing its early medical use.
