EFR 908: How to Use Methylene Blue Safely for Energy, Recovery & Brain Health with Dr. Scott Sherr

In this second part of the conversation, Dr. Scott Sherr returns to unpack one of the most fascinating compounds in modern mitochondrial medicine — methylene blue. Once used as the first FDA-approved antimicrobial drug, methylene blue is now being rediscovered as a powerful mitochondrial optimizer that helps the body both produce and detoxify energy at the same time. Dr. Sherr breaks down how it enhances ATP production, improves focus, endurance, and recovery, and even helps with travel fatigue and brain fog. He explains how methylene blue works at the cellular level, why quality and dosing matter, and clears up common myths and controversies — including its relationship with nitric oxide, serotonin, and safety concerns. Whether you're an athlete, entrepreneur, or anyone seeking more consistent, sustainable energy, this episode will help you understand how to use methylene blue safely and effectively to support performance and longevity.

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Follow Chase @chase_chewning

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00:01 What Is Methylene Blue? — A 150-year-old molecule repurposed for mitochondrial health

02:13 From Blue Jeans to Medicine — The strange evolution from textile dye to the first FDA-approved drug

04:48 How It Works — The only compound that helps your cells both make and detoxify energy

06:52 Cyanide Antidote — How methylene blue restores mitochondrial function, even in toxin exposure

09:05 Real-World Results — Patient stories of fatigue recovery and performance optimization

11:34 Who It's For — From chronic illness to high performers seeking clean energy

13:31 Performance & Recovery Benefits — Endurance, anaerobic performance, and muscle recovery

16:18 Recovering Faster, Training Harder — How methylene blue enhances oxygen use and heart rate recovery

18:20 How to Cycle It — When and how often to take methylene blue for best results

20:31 Travel & Jet Lag Protocols — How methylene blue acts like oxygen at altitude and in airplanes

23:29 Methylene Blue for the Everyday Person — Calm, clean energy without the crash

26:33 The Importance of Quality & Purity — How to identify pharmaceutical-grade methylene blue and avoid contaminants

27:57 What to Look for in a Supplement — USP grade, certificates of analysis, and testing standards

30:51 Counterfeit Supplements & Amazon Scams — Why most methylene blue products don't meet purity claims

33:54 How to Take It — Solubility, timing, and why troches work best

36:09 Stacking with Red Light Therapy — Synergy between methylene blue and photobiomodulation

39:10 Dosage Guidelines — How to titrate, start low, and find your personal sweet spot

42:08 Who Should Avoid It — Blood pressure medications, SSRIs, pregnancy, and other contraindications

43:48 Clearing Up the Controversy — Why experts disagree on nitric oxide and serotonin effects.

45:23 The Nitric Oxide Debate — How dose determines whether methylene blue helps or hinders

47:51 Blue Brain Myths & Social Media Clickbait — The truth about the "blue brain" narrative

49:30 Final Thoughts — Safe dosing, cycling, and the future of mitochondrial optimization

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Episode resources:

• Part one "The #1 Thing Killing Your Mitochondra & How to Stop it Today"
• Watch and subscribe on YouTube
• Learn more at Troscriptions.com/everforward