#54 Metabolical Part II - Book Summary

Hello Wise Wordians,

Welcome back to another episode of ‘Wise Words Book Summaries’.

This week we are summarising ‘Metabolical’ by Robert Lustig which explores the relationship between processed foods and its overwhelming consequences on our health. 

In this episode, we cover topics such as:

• Debunking ‘Chronic Disease”
• The Eight Sub-cellular Pathways
• Pathways that are Foodable, Not Druggable
• What Does “Healthy” Really Mean?
• The Nutrition Mythology
• Pharmacokinetics and Pharmacodynamics

If any of these topics sound interesting to you then make sure to give it a listen, and if you enjoy what you hear, why not leave us a like, subscribe to our channel, or even better, let us know your thoughts in the comment section below, your feedback means so much to us and helps to improve our podcast.

In addition, if you fancy implementing any of the actionable ideas we mention in this episode, head over to our website at wisewords.blog where the ‘Metabolical’ book summary will be waiting for you.

Next week we will summarise the last section of ‘Metabolical’ so stay tuned.

We hope you enjoy it.

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Chapter:
00:00:00-Intro
00:01:01-Part II-Debunking ‘Chronic Disease”
00:01:25-The “Diseases” That Aren’t Diseases
00:06:53-Eight Sub-cellular Pathways
00:07:04-1. Glycation
00:07:42-2. Oxidative Stress
00:10:30-3. Mitochondrial Dysfunction
00:15:33-4. Insulin Resistance
00:18:19-5. Membrane Integrity
00:21:51-6. Inflammation
00:28:05-7. Epigenetics
00:40:00-8. Autophagy
00:42:37-Checkpoints Alpha, Bravo, Charlie: Nutrient-Sensing and Chronic Disease
00:43:02-Oxygen Is So Overrated
00:44:54-Two Metabolic Programs—One for Growth, One for Burning
00:48:41-Checkpoint Alpha: Phosphatidylinositol-3-kinase (PI3-kinase)
00:50:04-Checkpoint Bravo: Adenosine Monophosphate-kinase (AMP-kinase)
00:52:01-Checkpoint Charlie: Mammalian Target of Rapamycin (mTOR)
00:55:37-Foodable, Not Druggable
01:06:02-Diabetes—the Modern Scourge
01:11:59-Part III Notes from the Nutritional Battlefield-What Does “Healthy” Really Mean?
01:17:58-Nutrition mythology
01:24:26-Roberts Definition of “Healthy”
01:32:23-Nutrition “Unwrapped”
01:39:03-Pharmacokinetics and Pharmacodynamics
01:42:44-A Fibre Is Not a Fibre
01:47:28-A Carb Is Not a Carb
01:50:45-Carbs and Glycemic Index (GI)
01:54:34-A Protein Is Not a Protein
01:58:28-What and How Adults Eat
01:58:57-Here are why supplements can't help the 8 subcellular pathways
02:01:41-How to repopulate your unhappy gut:
02:02:55-What and How Children and Adolescents Eat
02:03:23-Breakfast Is a Dangerous Meal
02:04:43-Fructose Effects on the Brain
02:09:10-Debrief

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