Marketplace All-in-One "Organs on a chip" help researchers better understand diseases like endometriosis
Sep 1, 2025
In this engaging discussion, Linda Griffith, a bioengineer and director at MIT's Center for Gynepathology Research, shares her pioneering work on endometriosis using organ-on-a-chip technology. She explains how this innovative approach allows researchers to study living patient-derived tissue in the lab, moving beyond traditional animal models. The conversation dives into the complexities of endometriosis, the challenges of current treatments, and the promise of new therapies that could revolutionize women's reproductive health.
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Human Tissue Recreated In Microfluidic Chips
- Organs-on-chips recreate patient tissue in microfluidic platforms using cells from that patient.
- This approach builds lab models that reflect human disease features animal models miss.
Limits Of Animal Models For Human Immunology
- Animal models miss key aspects of human chronic inflammatory diseases and immunology.
- Studying human tissue in the lab captures features that make diseases uniquely human.
Patient Avatars Capture Key Biology
- Living patient avatars model key patient biology without replicating every body part.
- Researchers use systems biology to decide which components to include in the lab model.