The Effective Statistician - in association with PSI
Aspects of Placebo Response
Apr 15, 2024
Guest Alexander discusses various aspects of placebo response in clinical trials, including common misconceptions, factors driving the response, and its implications for clinical practice. The podcast explores strategies to enhance study design and manage placebo responses, emphasizing the importance of education and collaboration across industries.
15:54
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Quick takeaways
- Placebo response involves more than no treatment, influenced by patient perception.
- Factors such as treatment strength and physician-patient interactions impact placebo responses.
Deep dives
Understanding Placebo Response
Placebo response is often misunderstood as no treatment, but in reality, it involves providing a placebo treatment in addition to the standard care. The perception of patients plays a significant role in driving placebo response. Factors such as randomization ratio, strength of anticipated treatment, and pretreatment experience can influence the placebo effect. Physicians' perceptions and the intensity of patient interactions during the study also impact placebo response.
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