
 The Top Line Misconduct and the future of neurodegenerative disease research
 Nov 15, 2024 
 Matthew Schrag, a prominent neuroscientist at Vanderbilt University Medical Center, sheds light on a major research misconduct scandal involving Eliezer Masliah, whose manipulated imaging has tainted the credibility of neurodegenerative disease research. Schrag discusses the implications for Alzheimer’s and Parkinson’s drug development and highlights ongoing issues with treatments, including concerns over antibody efficacy and the need for innovative strategies. He stresses the critical importance of maintaining scientific integrity to ensure patient care and progress in this crucial field. 
 Chapters 
 Transcript 
 Episode notes 
 1  2  3  4  5 
 Intro 
 00:00 • 4min 
 Investigating Misconduct in Alzheimer's Research 
 03:55 • 2min 
 Critical Examination of Antibody Treatments for Neurodegenerative Diseases 
 05:44 • 3min 
 Challenges and Future Directions in Parkinson's Drug Targeting 
 08:37 • 2min 
 The Impact of Scandals on Neurodegenerative Research Integrity 
 10:22 • 5min 
