The Impact of Gluco-corticoids on Rheumatic Diseases

Gluco-corticoids are both beneficial and harmful in the treatment of rheumatic diseases. While they effectively control inflammation, they also have numerous long-term side effects, including decreased bone density, weight gain, and hyperglycemia. Recent clinical trials have aimed to identify the lowest effective dose and duration of glucorticoid treatment. Osteoporosis is a significant concern for patients on glucorticoids, and the American College of Rheumatology has developed guidelines to address and prevent glucorticoid-induced osteoporosis. Recommendations include early fracture risk assessment, the use of pharmacologic treatments, and individualized care for specific patient populations.