#27 Women's Reproductive Aging, Menopause, & Hormone Replacement Therapy | Dr. Jennifer Garrison

Nov 8, 2023

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Dr. Jennifer Garrison is a an Assistant professor at the Buck Institute for research on aging where she studies women's reproductive aging. In today’s conversation we discussed menopause and it’s effect on women’s health, hormone replacement therapy, and how increasing the number of quality eggs a woman has at age 40 by just 1% can be a game changer.

Episode Show Notes: https://livelongerworld.com/p/jgarrison

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DR. JENNIFER GARRISON LINKS: Lab: http://garrisonlab.com/ Donate to her research: https://gcrle.org/ CONNECT WITH AASTHA, LIVE LONGER WORLD: Twitter: https://twitter.com/aasthajs Newsletter: https://livelongerworld.com/ Instagram: https://www.instagram.com/aasthajs/ Airchat: https://www.getairchat.com/aasthajs

TIMESTAMPS: 00:00 Intro 1:38 Jennifer Garrison Intro 2:32 Ovarian aging & health risks 5:23 Progression of Ovarian aging 8:49 Menopause and negative health effects 10:34 Hypothalamus & Mind body communication 14:40 Reproductive & Equality Initiatives 18:21 Biological Clock for Reproductive aging 20:20 Tweaking hormonal cues 22:07 Number of eggs vs. Quality of eggs 25:00 Genetics in ovarian aging 26:21 Understanding family history 27:39 Evolutionary benefit to Menopause? 32:33 Hormone Replacement Therapy (HRT) & its benefits 38:28 Narrow window for HRT 40:08 Perimenopause 42:56 Women’s health funding 45:14 Average age girls start menstruating is declining 49:10 PCOS 52:42 Athletes and irregular cycles 56:36 Individualized menopause symptoms 1:00:38 Exercise and ovarian aging 1:02:00 Support Jennifer's work

Episode Show Notes: https://livelongerworld.com/p/jgarrison POPULAR EPSIODES: - Richard Miller on Longevity Supplements: https://youtu.be/42PzfNs9egA - Matt Kaeberlein on Rapamycin: https://youtu.be/BL67DhNepfg - Michael Levin on Bioelectric Signals for Longevity: https://youtu.be/XboYI_wxDr8 - Nir Barzilai on Metformin & Centenarians: https://youtu.be/YlkBE8N7sl8 - Morgan Levine on Epigenetic Clocks: https://youtu.be/am3YKiTpCHo

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Aging is universal. Let's unite in this fight. Stay in good health - Aastha.