Freely Filtered 047: CHAP, time to treat hypertension in pregnancy

The Filtrate:

Joel Topf

Nayan Arora

Sophia Ambruso

Swapnil Hiremath

Josh Waitzman

Special Guest:

Natalie Bello Director of Hypertension Research at Cedars Sinai

Editor:

Nayan Arora

Show Notes:

NephJC summary of CHAP

CHiPS TV show

CHIPS study: Less-Tight versus Tight Control of Hypertension in Pregnancy

Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International Guidelines (Pubmed)

SFLT in preeclampsia from where else but NephMadness and here.

Aspirin Use to Prevent Preeclampsia and Related Morbidity and MortalityUS Preventive Services Task Force Recommendation Statement (JAMA)

The NNT for aspirin in pregnancy is like a relationship on Facebook, it’s complicated.

Astrologic signs as predictor of aspirin effectiveness in Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group (Pubmed)

ACOG revises the guidelines on hypertension: Clinical Guidance for the Integration of the Findings of the Chronic Hypertension and Pregnancy (CHAP) Study

Meta-analysis showing treating blood pressure in pregnancy didn’t help. Antihypertensive drug therapy for mild to moderate hypertension during pregnancy.