Core IM | Internal Medicine Podcast #133 Post-Kidney Transplant: 5 Pearls Segment
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Aug 16, 2023 Topics discussed in this podcast include side effects of tacrolimus and mycophenolate, medication interactions, unique causes of acute kidney injury in transplant recipients, viral syndromes associated with fever, signs and symptoms of rejection, immunosuppression, medication reconciliation, infections in transplant patients, transplant rejection, cancer after transplant, the role of steroids in post-kidney transplant maintenance, medication management and adherence, challenges and treatment options for hydro-nephrosis, viral serologies and risk factors, and cancer screening in immunocompromised patients.
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Explain Immunosuppression
- Explain immunosuppression by saying the body treats the new kidney like an infection.
- Emphasize that immunosuppressants must be taken lifelong.
Tacrolimus Trough Levels
- Get tacrolimus trough levels 11 hours and 15 minutes before the next dose.
- Never stop tacrolimus due to a random trough level.
Calcineurin Inhibitor Side Effects
- Tacrolimus and cyclosporine can cause neurotoxicity, hypertension, and new onset diabetes (NODAT).
- Tacrolimus may cause hair loss, while cyclosporine may cause hair growth.