BMJ Best Practice Podcast Sepsis in adults
13 snips
Feb 26, 2024 Delve into the intricacies of diagnosing sepsis in adults, including immune responses and identifying sepsis in immunocompromised patients. Learn about tailoring diagnostic tests, promptly administering antibiotics, managing comorbidities, and addressing common concerns among trainees. Explore challenges in sepsis diagnosis and the importance of education for enhanced patient care.
AI Snips
Chapters
Transcript
Episode notes
Sepsis Defined By Dysregulated Host Response
- Sepsis is organ dysfunction from a dysregulated host response to infection.
- The definition requires an infection triggering immune-driven organ damage.
Two Faces Of Sepsis Presentation
- Sepsis can present with either hyperinflammatory or hypoinflammatory patterns.
- Many patients, especially immunocompromised, lack fever or leukocytosis despite severe sepsis.
Target Tests To Suspected Infection Site
- Direct diagnostic tests to the suspected infection site based on history and exam.
- Use chest imaging for pneumonia and lumbar puncture for suspected meningitis.