Join Naturopath Sandra Villella and our Ambassador Lisa Costa-Bir as they discuss and dispel some of the myths around Premenstrual Dysphoric Disorder (PMDD), a condition that affects and estimated three to eight percent of women. PMDD, both a gynaecological and mental health disorder is an under-recognised disorder that is riddled with misconceptions around the role of excess oestrogen. Together, Sandra and Lisa discuss the latest research including PMDD sufferers' sensitivity to normal hormone fluctuations and the important role of progesterone the relationship with neuroactive steroids like pregnenolone, oestradiol, progesterone, and corticosteroids. The roles of allopregnanolone and serotonin in PMDD are discussed, as well as prescribing solutions including saffron, vitamin B6 (including dosages to prevent peripheral neuropathy) and vitex, and protocols to boost clinicians prescribing confidence. The conversation is rounded off by nutritional strategies and light therapy's serotonin-boosting potential shown to be beneficial for PMDD symptom management. Find today's transcript and show notes here: https://www.fxmedicine.com.au/podcast/pmdd-debunked-and-demystified-lisa-costa-bir-and-sandra-villella Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://pages.blackmores.com.au/FXM-signup.html ***DISCLAIMER: The information provided on FX Medicine is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***