VJHemOnc Podcast
ISA 2022: meeting highlights and recent updates in amyloidosis
Oct 21, 2022
Experts Shaji Kumar and Ashutosh Wechalekar discuss highlights from the ISA 2022 meeting, including diagnostic approaches in AL amyloidosis, advances in imaging techniques, and the role of stem cell transplantation in the era of daratumumab-based therapies.
12:37
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Quick takeaways
- The podcast highlights the advancements in imaging techniques for amyloidosis, including sensitive imaging techniques like cardiac MRI scans and whole-body imaging that improve early detection and understanding of the disease.
- The podcast emphasizes the significance of light chain glycosylation as a risk factor for the progression of light-chain amyloidosis and the need to rapidly reduce light chain levels to improve patient outcomes.
Deep dives
Evolution of Diagnostic Approaches and Improved Imaging Techniques in Light-Chain Amyloidosis
The podcast highlights the evolved diagnostic approaches in light-chain amyloidosis and the advancements in imaging techniques. The experts discuss how sensitive imaging techniques, such as cardiac MRI scans and specific tracers, have improved the ability to track amyloid in different organs. They also emphasize the potential for whole-body imaging to replace traditional biopsies and aspirates for detecting amyloid deposition. The experts anticipate that these imaging advancements will facilitate early detection and better understanding of neuropathic amyloidosis as well.
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