The Internet Book of Critical Care Podcast
IBCC Episode 43 Clostridium Difficile
Jul 5, 2019
In this episode, the hosts discuss various aspects of Clostridium difficile (C-diff) infection, including prevention, lab tests, risk factors, and potential therapies. They emphasize the importance of hand hygiene, precautions, and isolating patients with C-diff. They also explore the use of tigecycline, bezlotoxin map, and microbiota transplantation as potential treatments in the ICU.
24:18
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Quick takeaways
- Limiting antibiotic use and avoiding prophylactic antibiotics for unnecessary procedures can help in preventing C-diff infections.
- Testing for C-diff should have a low threshold, especially in critical care units or emergency rooms, and should be considered even in patients without diarrhea.
Deep dives
Prevention of C-diff infection
Limiting antibiotic use and avoiding prophylactic antibiotics for unnecessary procedures can help in preventing C-diff infections. Probiotics, such as saccharomyces boulardii, were previously recommended for prevention, but recent literature has become unclear about their effectiveness.
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