CoinDesk Podcast Network Building Autonomous Health Systems in the Age of AI with Bryan Johnson
Jan 13, 2026
Bryan Johnson, founder and CEO of Blueprint and Don't Die, is on a mission to reverse human aging using systems and technology. He discusses how FinTech principles and the philosophy of crypto intertwine with longevity. Johnson shares his vision of 'Autonomous Health,' where AI manages our bodies through bio-algorithms. He also delves into his personal journey to defy aging and connects it to broader ideologies. His goal? To operationalize immortality by 2039, making healthy choices automatic and exploring practical tips for enhancing life.
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Payments Were A Means To An End
- Bryan started Braintree to free himself from trading time for money and enable species-level projects.
- He used payments as a means to build wealth quickly, then pivoted toward longevity work after selling.
Crypto And Longevity Share A Philosophy
- Bryan Johnson sees a philosophical overlap between crypto and longevity through a shared rejection of inflation and aging.
- He argues both movements are driven by tech-native minds seeking to extend systems and life.
The Future Is Increasingly Unpredictable
- Johnson warns the future is less predictable due to computational irreducibility and emergent intelligence.
- That unpredictability makes planning harder and favors adaptable, automated systems.
