Navigating Neuropsychology 120| Apathy and Agitation in Neurodegenerative Diseases – A Conversation With Dr. Krista Lanctôt
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Jun 1, 2023 Dr. Krista Lanctôt, an expert in neuropsychiatric symptoms in older adults with neurodegenerative diseases, discusses apathy and agitation. The topics include diagnose criteria, epidemiology, relation to neuropathology, different treatment approaches, and challenges faced by caregivers.
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NPS Emerge Early And Predict Progression
- Neuropsychiatric symptoms (NPS) appear early and change with disease stage, predicting progression from normal to MCI and dementia.
- Apathy and agitation particularly increase risk of conversion and become more prevalent as Alzheimer's advances.
Use The MBI Checklist For Early Behavioral Risk
- Use the Mild Behavioral Impairment (MBI) checklist to detect sustained late-life neuropsychiatric changes lasting ≥6 months.
- Screen caregivers with the 34-item MBI-C to identify people at higher risk of progression to dementia.
Screen Broad, Then Add Specific Scales
- Start with the Neuropsychiatric Inventory (NPI) for broad screening and add symptom-specific scales once identified.
- Use AES, DAIR, CMAI, PHQ-9 or GAD-7 depending on the targeted symptom for sensitivity and change detection.