Maintenance Phase cover image

Maintenance Phase

Ozempic

Oct 10, 2023
Mike and Aubrey discuss the sensational claims of Ozempic, the potential end to the Obesity Epidemic. They delve into the origins and function of the drug, as well as conflicting views on pharmaceutical companies and weight loss treatments. They explore the efficacy and side effects of semagitide trials, and the frustrating experiences of fat individuals seeking medical advice. The podcast also examines Novo Nordisk's marketing practices and critiques the reporting of influencer partnerships and body positivity.
58:21

Podcast summary created with Snipd AI

Quick takeaways

  • Clinical trials show that Ozempic can lead to significant weight loss and improvements in health markers, but real-world studies suggest less pronounced results and higher dropout rates.
  • Marketing campaigns for Ozempic have been criticized for reinforcing stereotypes and stigmatizing fat individuals, highlighting the need to prioritize their perspectives in the conversation about weight loss drugs.

Deep dives

The effectiveness and limitations of some Aglitide for weight loss

Clinical trials show that some Aglitide, the active ingredient in Ozempic and Wegovii, can lead to significant weight loss, with roughly 50% of people losing 10-15% of their body weight and one-third of people losing more than 20%. The trials also demonstrate improvements in blood pressure, cholesterol, and A1C levels, along with potential reductions in heart attacks and strokes. However, real-world studies suggest that the weight loss results may be less pronounced than those seen in the trials. Furthermore, dropout rates in the real world are higher, and weight regain is common once the drug is discontinued. These findings challenge the notion that the drugs will lead to the end of obesity and highlight the importance of considering individual experiences and limitations of the medications.

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