Sensible Medicine cover image

Sensible Medicine

Mandrola and Prasad are back

Dec 17, 2023
Topics discussed include the approval of a drug for postpartum depression, effectiveness of drug classes in treating various conditions, critique of FDA's regulatory process, examining the role of stenting and medication in angina treatment, challenges in pragmatic trials and the detection of gravitational waves, the cultural difference between medicine and physics, and the failure of ECMO trials.
50:55

Podcast summary created with Snipd AI

Quick takeaways

  • The need for more rigorous studies to evaluate the efficacy and safety of new medications, including Zoranalone for postpartum depression.
  • The importance of further research to determine the appropriate use of stenting in stable angina patients, considering the limitations of the Orbita 1 and Orbita 2 studies.

Deep dives

Podcast Episode Highlights: Sensible Medicine Podcast

In this podcast episode, the hosts discuss various topics including a new postpartum depression drug called Zoran alone, the Orbita 1 and Orbita 2 studies on stenting for stable angina, the difference between physics and medicine, and the challenges of the FDA approval process. The hosts critically analyze the studies, questioning the design, methodology, and the interpretation of the results. They highlight the need for more evidence-based practice in medicine and the importance of conducting rigorous trials to determine the efficacy and safety of medical interventions.

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