FFP EP. 12 | From Princeton to the Nobel Prizes — How FFP Started + 2025 Nobel Recap

After a packed week of Nobel Prize coverage, Lester and Krishna look back on how From First Principles began and why they built it as an “ESPN for Science.” They revisit 2025’s Medicine, Physics and Chemistry winners and discuss why fundamental research and immigration policy are core to America’s scientific edge.

Quick note: this week’s episode is in vertical format because of a technical hiccup during recording — back to widescreen next week!

Summary

• Origin Story — Two Princeton friends from different continents unite around a shared love of science and storytelling.
• The Mission — Creating an “ESPN for Science” that celebrates research and the people behind it.
• Nobel Follow-ups — Medicine (Tregs and non-immune roles), Physics (macroscopic quantum tunneling and quantum supremacy), Chemistry (MOFs and industrial scaling).
• Funding + Immigration — Why public research grants and curating global talent are vital to scientific leadership.

Show Notes

• Nobel Prize Press Release (2025 Medicine)
• Nobel Prize Press Release (2025 Physics)
• Nobel Prize Press Release (2025 Chemistry)
• Nature Genetics (2001) — FOXP3 Mutation Causes Dysregulation
• Nature (1999) — MOF-5 Discovery (Omar Yaghi et al.)
• Google Quantum AI Lab — Quantum Supremacy (Nature, 2019)