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Okay this is a big one - a really big one.
Professor Vladimir Subbotin has published multiple papers on his groundbreaking hypothesis, which turns the LDL / ApoB /LDLp dogma on it's head.
Do LDL particles really invade your artery wall - attacking from the blood flowing through your arteries?
Or is this hypothesis completely incorrect - and not in line with the actual science and pathology of Atherosclerosis? Note that Subbotin's hypothesis is not PROVEN - for example there may be early deposition from lumen side, with the adventitial VV being far more important in the milieu nonetheless. Also, even if early deposition from the lumen side does occur - it is still only because of the Root Causes we list! So it's still moot in any case! ;-)
Find out in this fascinating Episode!
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VIDEO PODCAST WITH SLIDES: https://www.youtube.com/watch?v=jv9qXM2qLxo&feature=youtu.be