This is second part of the conversation with Randy Schekman. He is an  investigator of the Howard Hughes Medical Institute and a Professor of  Cell and Developmental Biology in the Department of Molecular and Cell  Biology at the University of California at Berkeley. He was awarded the Nobel Prize in Physiology or Medicine in 2013 for his  role in revealing the machinery that regulates the transport and  secretion of proteins in our cells. He shares the prize with James E.  Rothman of Yale University and Thomas C. Südhof of Stanford University. 

In this conversation we talk about his work on scientific publishing,  his suggestions for  early-career researchers and his experience on Parkinson's project.  

Listen to part I here: https://youtu.be/bl1uG4PbTOE 

Find more about Randy's work: http://mcb.berkeley.edu/labs/schekman/ 

Randy's biography: https://www.nobelprize.org/prizes/medicine/2013/schekman/facts/ 

Episode links: 

Website: https://www.reasonwithscience.com/home/the-noble-journey-with-randy-schekman-ii 

Youtube: https://youtu.be/MNjfkoutAhQ 

Spotify:  

Apple podcast:   

Google podcast:    

Follow Reason with Science:   

Website: https://www.reasonwithscience.com/   

Youtube: https://www.youtube.com/channel/reasonwithscience   

Spotify: https://open.spotify.com/show/5qFLGsPWjL4GAGidmF2nKh   

Apple podcast: https://podcasts.apple.com/us/podcast/reason-with-science/id1641776894   

Google podcast: https://podcasts.google.com/feed/aHR0cHM6Ly9hbmNob3IuZm0vcy9iMjMyNDZlOC9wb2RjYXN0L3Jzcw

Timestamps: 

00:00:00 Introduction 

00:00:49 How to select a scientific question? 

00:05:13 Bold ideas survive in science!   

00:06:50 Importance of collaboration in science 

00:12:24 ASAP project model for early career researchers  

00:13:03 Change in the evaluation process 

00:19:25 How to understand quality of science? 

00:24:31 Parkinson's project (ASAP)  

00:28:02 Why scientific publishing can change?  

00:29:43 Understanding of scientific method to improve scientific publishing! 

00:31:37 Any shift in pressure of publishing?  

00:32:58 More about Parkinson's project (ASAP) 

00:38:38 Role of unstructured proteins in neurodegenerative diseases  

00:41:41 Unstructured proteins are the next problem! 

00:42:38 No markers for Parkinson's so far! 

00:43:50 Causes of Parkinson's 

00:45:06 What can be a potential cure of Parkinson's?  

00:47:12 Thank you!  

More Talks from Randy: 

TEDx on scientific publishing: https://youtu.be/-N4Mb8tsyT8 

iBiology: https://youtu.be/xvjUgTKlKyU 

Nobel prize inspiration initiative lecture: https://youtu.be/Udg6bYkBtX8  

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