BMJ Best Practice Podcast Mumps
Nov 6, 2025
In this insightful discussion, Dr. Kristine Macartney, Director of the National Centre for Immunisation Research and Surveillance, sheds light on the resurgence of mumps, a disease once largely controlled by vaccination. She explains the nuances of diagnosing mumps, including testing methodologies like PCR and serology. Dr. Macartney also addresses vaccine effectiveness and the importance of herd immunity, while tackling common misconceptions about vaccine safety. The conversation emphasizes the critical role of vaccination and public health in preventing outbreaks.
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Classic Presentation And Course
- Mumps is an acute viral illness best known for parotid gland swelling causing a painful 'chipmunk' appearance.
- Symptoms usually start with fever, headache and body aches and parotitis often lasts about a week.
Serious Complications Are Real
- Mumps can cause serious complications including orchitis, meningitis, hearing loss, pancreatitis and ovarian inflammation.
- Orchitis occurs in about a third of post-pubertal males and can rarely lead to subfertility or infertility.
Confirm Diagnosis With Timed Tests
- When mumps is uncommon, confirm diagnoses using PCR from a buccal swab or serology with correct timing.
- Consult your laboratory or infectious disease specialist because vaccinated patients' serology can be hard to interpret.