The Incubator #375 - đźź CHNC 2025 COVERAGE - EXPLORE projects HOT TOPICS! CAKUT risk calculator and TH in the 33-35 weeks GA!
This episode features Dr. Sofia Isabel Perazzo (Children’s National Hospital) and Dr. Rakesh Rao (St. Louis Children’s Hospital) discussing a CHNC Explore analysis of intestinal stricture formation following surgical necrotizing enterocolitis (NEC). Using 15 years of CHND data, they examined over 2,400 surgical NEC cases, finding an overall stricture incidence of about 31%, with striking inter-center variability (24–38%). Lower gestational age, stoma creation, and combined drainage-laparotomy increased risk, while peritoneal drainage was protective. Hispanic ethnicity was associated with lower risk. Although their predictive model (AUC 0.67) was modest, the findings offer valuable benchmarks for parent counseling, quality improvement, and hypothesis generation.
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