Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management.
Learn more about C5 Research at Cleveland Clinic.
https://my.clevelandclinic.org/research/c5research
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Cardiac Consult: A Cleveland Clinic Podcast for Healthcare Professionals