Episode 154: Is Seed Based Cultivation the Future of Cannabis? - with Dr. Matthew Indest

n this conversation with plant scientist and commercial cultivation strategist Dr. Matthew Indest, we explore the emerging frontier of seed-based cannabis production and what it would take for the industry to move beyond clonal propagation.

We cover:

The agronomic upside of seed-grown plants (disease resistance, vigor, adaptability, cost savings)

The scientific and operational barriers preventing widespread seed adoption

How genetic stability, inbreeding depression, and trait selection differ between cannabis and traditional crops

Data-driven cultivation strategies for evaluating new seed lines

Whether seed-based production can truly rival clonal systems for consistency and top-tier flower quality

What the next decade of cannabis breeding and cultivation might look like

About Dr. Indest:
Matthew holds a Ph.D. in plant science and has spent more than a decade bridging academic research with applied cannabis production. He has led breeding and cultivation programs across indoor, greenhouse, and outdoor operations and focuses on developing high-performing cultivars and integrated, data-backed production systems.

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