PCOS symptoms often intensify after 30 due to compounding insulin resistance, adrenal stress patterns, and brain–ovary signaling changes. As estrogen and progesterone begin subtle shifts in the mid-30s, many women experience more anovulatory cycles, higher cortisol responses, and worsening androgen symptoms.

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On the Way #21: Feel your brain is not normal? Not a problem (according to this Brain Expert)