In this episode we discuss:

The criticism of Georgi regarding estrogen and cancer
The major point that Siim Land is missing when it comes to increasing NAD+
Why we think Dr. Berg is completely wrong on serotonin
Nutrition With Judy’s suggestion that thyroid issues on a carnivore diet are not caused by the lack of carbohydrates, and why we think this isn’t the case
Dave Asprey’s recommendation to drink orange juice and whether it’s for the right reasons

Timestamps:

0:00 – intro

1:10 – whether estrogen is a carcinogen

6:13 – estrogen’s role in driving weight gain and chronic diseases such as cancer, Alzheimer’s disease, and Type 2 Diabetes

8:03 – the dangers of synthetic progesterone (progestin) use

10:14 – the difference between estrone and estradiol and the problems with estrogen testing

16:14 – whether estrogen therapy should be used in post-menopausal women

17:17 – the difference between oral and transdermal estrogen use

24:44 – the connection between inflammation and estrogen production

27:57 – why estrogen levels are not actually low in post-menopausal women

37:59 – our take on Siim Land's post on NAD+ and mitochondrial uncoupling

48:25 – why intentionally seeking hormetic responses, like the activation of heat-shock proteins, should be avoided

50:37 – which form of CoQ10 is better: ubiquinone or ubiquinol

53:34 – what Siim Land and many others get wrong when it comes to raising NAD+

55:44 – does fasting and AMPK upregulation cause cancer?

1:00:29 – fat fuels cancer and why not to restrict sugar for cancer

1:09:56 – Dr Berg’s take that serotonin is the “happy hormone” – why we disagree

1:19:06 – serotonin’s role in driving chronic diseases and conditions including depression, anxiety, IBS, and cancer

1:27:24 – Nutrition with Judy claims that the low thyroid levels generally seen on the carnivore diet have nothing to do with a lack of carbohydrates

1:39:01 – how the rate of living theory changed mainstream medicine’s view that thyroid health is important

1:45:37 – how excessive exercise raises stress hormones, setting you up for weight regain

1:51:30 – why the combination of fasting and exercise is detrimental to our health

1:53:44 – how estrogen is used to fatten animals

2:02:42 – why Dave Asprey is talking about endotoxin and orange juice

2:07:00 – whether the sugar in orange juice feeds bacteria and increases endotoxin

2:09:40 – why the low-carb trend keeps resurfacing, despite the growing evidence against it

2:14:41 – where to find Georgi and IdeaLabs

Ep. 37 Open Source Project O-FISH with Sheeri Cabral