The Intern At Work: Internal Medicine

233. Marrow’s Most Wanted- An Approach to Pancytopenia

Apr 14, 2024
Dr. Laura Habib, a Hematologist-Oncologist, and Dr. Natasha Nathoo, an Internist, discuss the approach to pancytopenia. They cover topics like causes of pancytopenia, comprehensive evaluation, treatment options for Myelodysplastic Syndrome, and the importance of addressing underlying issues for effective management.
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INSIGHT

Bone Marrow and Hematopoiesis

  • Bone marrow, the body's blood cell factory, is located in specific bones.
  • Hematopoietic stem cells differentiate into various blood cell types.
INSIGHT

Understanding Pancytopenia

  • Pancytopenia, a decrease in all blood cell types, isn't a disease itself.
  • It indicates an underlying issue affecting bone marrow or peripheral blood cells.
ADVICE

Initial Assessment of Pancytopenia

  • Ensure the patient is stable, addressing potential life-threatening complications.
  • Document a thorough medical history, medication review, and symptom assessment.
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