BackTable Vascular & Interventional Ep. 582 PERT Consortium Recap: New Developments in PE with Dr. Jonathan Paul and Dr. Osman Ahmed
Oct 17, 2025
Dr. Jonathan Paul and Dr. Osman Ahmed, experts in interventional cardiology and radiology, share insights from the recent PERT Consortium in San Diego. They delve into cutting-edge developments in pulmonary embolism (PE) treatment, including advancements in thrombectomy devices and the importance of combined therapies. The conversation also highlights their collaboration at Flow Medical, focusing on a novel device that provides real-time pulmonary artery pressure feedback. Their passion for innovation and data-driven approaches promises a transformative future for PE care.
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PERT At An Inflection Point
- PERT is at an inflection point with many major PE trials finishing enrollment and soon to report results.
- Dr. Jonathan Paul expects the landscape to look very different within a year as those data publish.
Trials Driving Practice Change
- The field is waiting on multiple trial results like PEERLESS and RESCUE-II before practice patterns change.
- Early small studies (e.g., Rescue 2) are promising but need larger enrollment to be practice-changing.
Trend Toward Smaller Thrombectomy Catheters
- Companies compete by making smaller, lower-profile thrombectomy devices and adding novel mechanisms like vibration or jets.
- Whether smaller catheters can match larger-bore devices for big saddle PEs remains unanswered.