NFL Daily with Gregg Rosenthal

Week 12 NFL Picks with Cynthia Frelund

Nov 21, 2025
Cynthia Frelund, an NFL Network analytics expert, joins to break down Week 12 picks with confidence. They delve into the 49ers' defensive strengths against the Panthers and discuss Atlanta's potential as underdogs against the Saints. Cynthia also highlights Seattle's advantage over Tennessee, while Gregg emphasizes the Browns' defensive prowess against the Raiders. The duo wraps up with picks for the Falcons, Browns, and Seahawks, sharing insights on their reasoning and matchup advantages.
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INSIGHT

Why 49ers Projected To Contain Bryce Young

  • The San Francisco 49ers are favored because their defense limits 11-personnel rushing success.
  • Cynthia Frelund trusts the 49ers' overall defense and offense to control Bryce Young's impact.
ANECDOTE

Gregg's Thursday Line Ritual

  • Gregg Rosenthal shares that he waits until Thursday mornings to pick based on which lines 'speak' to him.
  • He contrasts that subjective approach with Cynthia Frelund's model-informed reasoning.
INSIGHT

Falcons Look Better Than Line Suggests

  • The Falcons are underpriced as road underdogs despite being the better roster.
  • Gregg Rosenthal cites Atlanta's stronger defense and matchup advantages vs. the Saints.
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