PSMA PET Scans work for Prostate Cancer with Dr. Alberto Vargas

Apr 8, 2025

Dr. Alberto Vargas, Vice Chair of Oncologic Imaging at NYU Langone Health, shares his expertise in prostate cancer imaging. He discusses how MRI, PET, CT, and particularly PSMA PET scans are revolutionizing detection and treatment. Vargas explains the benefits of PSMA PET scans in identifying recurrent disease at low PSA levels and the differences between various scan types. He delves into interpreting results, the potential for fewer invasive biopsies, and the future of imaging technology in prostate health, making it a vital listen for patients and caregivers.

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INSIGHT

MRI's Strength in Prostate Imaging

MRI uses magnetic fields and radiofrequency, providing detailed prostate anatomy without ionizing radiation.
It excels at showing prostate zones, capsule, and surrounding tissues better than CT or ultrasound.

INSIGHT

PSMA PET's Game-Changing Accuracy

PSMA PET scan uses a radioactive injection targeting prostate cancer cells, improving detection dramatically.
This scan finds metastatic and recurrent prostate cancer earlier and more accurately than prior PET tracers or bone scans.

ADVICE

When to Use PSMA PET Scans

PSMA PET scans are recommended primarily for intermediate to high-risk prostate cancer patients.
Using PSMA scans in low-risk or surveillance patients is not generally supported due to low spread likelihood.

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In this episode of the Dr. Geo Prostate Podcast, Dr. Geo welcomes Dr. Alberto Vargas, Vice Chair of Oncologic Imaging at NYU Langone Health and expert in prostate cancer imaging.

They dive deep into the evolving world of diagnostic tools—MRI, PET, CT, and PSMA scans—and how these technologies help detect, monitor, and guide treatment for prostate cancer. Dr. Vargas explains the difference between imaging modalities, when to use them, and how PSMA PET scans are changing the game in identifying recurrent and metastatic disease earlier than ever before.

Key topics covered:

MRI vs. PET vs. CT: what each scan shows and when it matters most
The rise of PSMA PET for finding prostate cancer at extremely low PSA levels
Why not all PET scans are the same, and how tracers like FDG, Axumin, and PSMA work
The potential future of prostate cancer diagnosis: fewer biopsies, more imaging
Limitations, false positives, and how imaging results are interpreted
The role of imaging in both first-time diagnosis and recurrence

Whether you're a patient, caregiver, or clinician, this episode offers valuable insight into how imaging helps guide smart, proactive decisions in prostate cancer care.

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DISCLAIMER: This audio is educational and does not constitute medical advice. This audio's content is my opinion and not that of my employer(s) or any affiliated company.

Use of this information is at your own risk. Geovanni Espinosa, N.D., will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video, including but not limited to economic loss, injury, illness, or death.