The Cribsiders S5 Ep112: The Re(n)al Truth Behind Proteinuria
Jun 19, 2024
Drs. Emily Zangla and Annie Kouri, hosts of the Kidney Chronicles Podcast, dive deep into the multifaceted world of proteinuria. They cover its implications in chronic kidney disease and urinary tract infections, making sense of tests like the urine protein to creatinine ratio. Their discussion includes personal anecdotes tied to clinical challenges in pediatric nephrology, emphasizing the importance of intuition in diagnosing conditions. They also share essential management strategies for pediatric kidney issues, highlighting recent advancements in testing and treatment.
AI Snips
Chapters
Transcript
Episode notes
Confirming Proteinuria
- Always obtain a urine protein to creatinine ratio if urinalysis shows protein.
- Dipstick tests are less accurate, only measuring albumin and having high false negative/positive rates.
Protein Types in Urine
- Dipstick tests primarily measure albumin, a surrogate for glomerular protein.
- Other proteins, like tubular proteins (retinal binding protein, beta-2 microglobulin), also matter but are less often measured.
Initial Testing for Proteinuria
- Order a urinalysis with protein to creatinine ratio as the first step for suspected proteinuria.
- A urinalysis alone provides valuable information about other urinary components.