Back from the Abyss: Psychiatry in Stories Sex Hormones and Psychiatric Illness with Dr. Neill Epperson
Feb 28, 2025
In this engaging conversation, Dr. Neill Epperson, Chair of Psychiatry at the University of Colorado, dives into the fascinating relationship between sex hormones and psychiatric health. They discuss postpartum mental health challenges and the complexities of individual hormone responses. The role of estrogen in brain function is highlighted, showcasing its impact on cognitive abilities. They also explore menopause, hormonal therapy, and the need for tailored treatments. Overall, it's a compelling look at how hormones intricately weave into mental health and wellness.
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Hormonal Sensitivity
- Hormone levels themselves are not the direct cause of PMDD or similar issues.
- It's about the brain's sensitivity and response to normal hormonal fluctuations.
Brain Flexibility and Pregnancy
- The female brain exhibits remarkable flexibility to accommodate hormonal shifts throughout life.
- Pregnancy can alter the brain's response to hormones, sometimes triggering PMS or PMDD post-childbirth.
Estradiol and Childhood Adversity
- Dr. Epperson conducted a study on menopausal women with cognitive concerns.
- Estradiol improved cognitive function in women with high childhood adversity, highlighting personalized medicine's importance.