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The Readout Loud
311: Fauci's memoir, Alnylam's tenuous trial, and a mid-year review
Jun 20, 2024
STAT reporter Jason Mast discusses Fauci's memoir 'On Call' and Alnylam's trial data. They analyze biotech market trends for the year. Fauci's interactions with Presidents, concerns about science politicization, and the unique journey to access his book are highlighted.
34:10
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Quick takeaways
- Alnylam's clinical trial assesses Vutri's impact on cardiovascular outcomes in a second chance for efficacy.
- Fauci's memoir highlights his challenging relationship with Trump and the interplay of politics and science in healthcare.
Deep dives
Al Nylum's Crucial Vutri Study on ATTR-CM
An intense focus is on Al Nylum's significant cardiovascular outcome study, experimenting with Vutri, an RNA silencing drug aimed at treating ATTR-CM. This trial intends to assess Vutri's impact on patient mortality and cardiovascular outcomes, particularly after a previous failed drug attempt by the company. Highlighting a second chance for efficacy, the trial involves comparing Vutri to Pfizer's stabilizer pill, with a vital key being the combination treatment's effectiveness.
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