Dr. Joseph Mercola - Take Control of Your Health Personalized Vitamin D Levels Cut Repeat Heart Attack Risk by Half
Dec 23, 2025
A groundbreaking study reveals that optimizing vitamin D levels can slash the risk of repeat heart attacks by over 50%. Many adults with heart disease initially had low vitamin D, with more than half needing high daily doses to achieve protective levels. Vitamin D helps combat inflammation and supports blood vessel function. Key recommendations include regular testing, sensible sun exposure, and a diet free from seed oils. Pairing vitamin D with magnesium and K2 enhances its protective effects, while exercise further strengthens heart health.
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Personalized Vitamin D Cuts Repeat Heart Attack Risk
- The Target-D trial personalized vitamin D dosing for patients with prior cardiac events and monitored levels over time.
- Those who reached the 40–80 ng/mL range had markedly better outcomes than unmonitored patients.
Deficiency Was Common And Required Ongoing Management
- Most participants began below the protective threshold, with 85% under 40 ng/mL at baseline.
- Ongoing testing and dose adjustments, not a single dose, produced the benefit.
Use D3 With Magnesium And K2; Expect Higher Doses
- Use vitamin D3 supplementation (not D2) and pair it with magnesium and vitamin K2 to improve activation and arterial safety.
- Expect many people to need doses >5,000 IU/day to exceed 40 ng/mL.