Acne is one of the most common skin conditions, affecting about 80% of all teens. While some teens will only experience mild symptoms, others may develop scarring, hyperpigmentation and negative psychosocial effects. Amanda Shepard-Hayes, MD, an Attending Pediatrician specializing in dermatology at Children’s Hospital of Philadelphia, discusses the importance of recognizing and treating this condition; the combination of factors that cause acne including hormone level changes during puberty or when certain drugs (i.e., corticosteroids, oral birth control) are started or stopped; the different types of acne lesions, and when distribution patterns may indicate a more serious health issue; treatment goals and therapies including topical and systemic medications. In many cases, combination therapy is appropriate, which includes low-dose benzoyl peroxide to kill the bacteria and tretinoin to halt the development of new acne lesions. Recurrent acne that occurs in young children (aged 1 to 7), or in unusual places (like the groin area), should be sent for further evaluation. Published July 2021. This podcast is for general informational and educational purposes only and is not to be considered as medical advice for any particular patient. Clinicians must rely on their own informed clinical judgment in making recommendations to their patients. ©2021 by Children's Hospital of Philadelphia, all rights reserved.