The Capitalism and Freedom in the Twenty-First Century Podcast Jay Bhattacharya on the NIH as An Innovation Accelerator | Hoover Institution
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Oct 13, 2025 
In a deep dive with Jay Bhattacharya, the former Stanford professor and current NIH Director, the discussion spans his vision for transforming the NIH into an innovation powerhouse. He addresses the replication crisis in science, emphasizing the need for reliable findings and new funding models for replication studies. Bhattacharya also highlights changing metrics for scientist productivity and revitalizing public trust in health research. He explores AI's role in biomedical advancements and unveils a new policy to reduce animal testing, advocating for ethical research alternatives.
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NIH's Core Mission Reaffirmed
- Jay Bhattacharya views the NIH's mission as advancing health and longevity and restoring public trust after the pandemic.
- He argues NIH must refocus on research that translates to better national health outcomes.
Replication Crisis Is A Systemic Problem
- Bhattacharya says much published science is unreliable due to hard problems and weak statistical standards.
- He identifies replication failure and publication bias as systemic, not mainly fraud.
Make Replication The Standard Of Truth
- Fund replication, reward pro-social scientific behaviors, and create places to publish replications so replication becomes the standard of truth.
- Use PubMed integration and AI summaries so replication evidence is visible alongside original papers.
