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In 1983 Dr. Brian P. LeSage earned his doctor of dental surgery degree from the University of Maryland, Baltimore College of Dental Surgery. He graduated magna cum laude and was inducted into the Omicron Kappa Upsilon National Dental Honor Society. And he completed a general residency program at the University of California, Los Angeles, School of Dentistry.

He began private practice in Washington, D.C., with an emphasis on esthetic and reconstructive dentistry. He relocated to Beverly Hills and, in 1990, established the Beverly Hills Institute of Dental Esthetics, where he practices with his wife, Dr. Afsaneh Malaekeh.