The Brain Health Revolution Podcast
Shifting Perspectives: Hormone Replacement Therapy, Menopause, and the Dementia Dialogue
Jul 21, 2023
Explore the connection between hormone replacement therapy and dementia risk. Discuss the impact of hormones on brain development and resilience. Highlight the complexities of hormone therapy and its impact on brain health. Examine the effects of menopause and hormone replacement therapy on sleep, cognition, and Alzheimer's risk.
52:57
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Quick takeaways
- Hormone replacement therapy, specifically estrogen and progesterone replacement, has been associated with a higher risk of developing Alzheimer's disease in women, contradicting previous studies.
- Women are at a higher risk of developing Alzheimer's disease compared to men, and factors such as longer lifespan, hormonal changes, and lower access to education contribute to this disparity, emphasizing the need to prioritize brain health in women.
Deep dives
Hormone Therapy and Alzheimer's Risk: A Complex Relationship
Hormone therapy, specifically estrogen and progesterone replacement, has been associated with a higher risk of developing Alzheimer's disease in women. This finding contradicts previous studies that suggested hormone therapy could be protective against cognitive decline. The duration of hormone therapy usage appears to be a crucial factor, with longer-term use associated with an increased risk. However, due to the contradictory findings and limitations of the studies, further research is needed to fully understand the relationship between hormone therapy and Alzheimer's risk. Women going through menopause and considering hormone therapy should consult with their healthcare providers to weigh the benefits and potential risks.
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