The Incubator

#308 - [Journal Club Shorts] - ๐Ÿ“Œ Sigh Breaths for HFOV: Yay or Nay?

May 11, 2025
Discover the intriguing findings on the impact of intermittent sigh breaths during high-frequency oscillatory ventilation for preterm infants. A randomized crossover study reveals potential benefits like improved lung volume and oxygen saturation. However, the research calls for more investigation regarding long-term safety. Tune in for insights that could shape future neonatal care practices!
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INSIGHT

Benefits of Sigh Breaths on HFOV

  • Sigh breaths during high-frequency oscillatory ventilation (HFOV) increase end-expiratory lung volume, especially in dependent lung regions.
  • They improve oxygenation without significantly altering mean airway pressure, showing promising physiological benefits.
INSIGHT

EIT as a Lung Monitoring Tool

  • Electrical impedance tomography (EIT) enables non-invasive, bedside monitoring of regional lung volume changes in preterm infants.
  • This tool provides detailed lung aeration visuals useful for assessing ventilation strategies like sigh breaths.
ADVICE

Use Intermittent Sigh Breaths Carefully

  • Consider using intermittent sigh breaths three times per minute with a one-second inspiratory time during HFOV to facilitate lung recruitment.
  • Balance the benefits with caution as safety and long-term outcomes are not yet well studied.
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