Pre PACES Podcast

#105 SLE

8 snips
Jan 19, 2025
Dr. Richard Haigh, a consultant rheumatologist with a focus on vasculitis, sheds light on systemic lupus erythematosus (SLE) and its myriad symptoms. He discusses the challenges of diagnosing SLE, including its overlap with other autoimmune diseases. The conversation delves into lifestyle impacts, particularly smoking, on disease progression, and the importance of thorough patient history-taking. Dr. Haigh also shares insights on effective management strategies, diagnostic markers, and the unique considerations for treating young women with lupus.
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INSIGHT

SLE Is A Multisystem 'Great Mimic'

  • SLE is a multisystem autoimmune inflammatory disorder that can affect most tissues and organs.
  • It commonly presents in many guises, making it the 'great mimic' in medicine.
ANECDOTE

Referral Often Starts With Positive ANA

  • Many referrals start with a positive ANA after vague symptoms like fatigue and arthralgia.
  • Rheumatology clinics often see letters asking, 'has this patient got lupus?'.
ADVICE

Ask About Photosensitivity And Characteristic Rashes

  • Ask explicitly about photosensitivity and rashes, especially on the face, shawl area and backs of hands.
  • Look for rashes that persist days-to-weeks and spare the nasolabial folds.
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