TWiV 1210: Clinical update with Dr. Daniel Griffin

Apr 19, 2025

Dr. Daniel Griffin, a physician and infectious diseases researcher, dives into critical updates on public health. He discusses alarming funding cuts to institutions like the NIH and CDC and their impact on disease prevention. The conversation highlights rising concerns regarding measles, deadly E. coli outbreaks, and the rising tides of long COVID. Dr. Griffin also provides insights on vaccination disparities and the importance of transparency in public health, making it a vital listen for anyone interested in infectious diseases.

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INSIGHT

Public Health Cuts Threaten Safety

Massive cuts to NIH, CDC, and FDA cripple public health and outbreak investigations.
Skilled workforce losses and lab closures will fuel reemergence of pathogens and worsen responses.

INSIGHT

Political Trust Gap in Science

Political ideology strongly influences trust in scientists in the U.S., with conservatives showing less trust.
Attempts to improve conservatives' trust in scientists were unsuccessful, indicating stable attitudes.

INSIGHT

Undisclosed Deadly E. coli Outbreak

FDA withheld details about a deadly E. coli outbreak linked to romaine lettuce that affected 15 states.
This lack of transparency is contrary to principles of public health and outbreak awareness.

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In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between Novavax and Pfizer COVID-19 vaccines, where to find PEMGARDA, provides information for Columbia University Irving Medical Center’s long COVID treatment center, where to go for answers to your long COVID questions, long COVID interventions, effects of long COVID in children and adolescents and a list of ongoing clinical trials for long COVID treatment.

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Links for this episode

Making America Healthy Again-purging of administrators at HHS (Politico)
Making America Healthy Again-purging of data (Politico)
Deep cuts of the federal government (NY Times)
Cutting NIH, CDC and HHS promotes chronic disease research(Washington Post)
Political ideology and trust in scientists in the USA(Nature Human Behavior)
US political conservatives have deep, unbudging suspicion of science, survey suggests(CIDRAP)
A deadly E. coli outbreak hit 15 states, but the FDA chose not to publicize it(NBC News)
Invasive meningococcal disease – Kingdom of Saudi Arabia(WHO)
The essential guide to understanding the differences between hajj and umrah (Marhabahaji)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Measles booster? (Washington Post)
How to stop an outbreak…….fire the experts (Washington Post)
Measles cases and outbreaks (CDC Rubeola)
Measles 159 in Texas…. (Texas Health and Human Services)
2025 Measles outbreak guidance (New Mexico Health)
Measles and rubella weekly monitoring (Government of Canada)
Measles vaccine recommendations from NYP (jpg)
NAFMA: North American Free Measles agreement…..(NY Times)
Get the FACTS about measles (NY State Department of Health)
Measles (CDC Measles (Rubeola))
Measles vaccine (CDC Measles (Rubeola))
Presumptive evidence of measles immunity (CDC)
Contraindications and precautions to measles vaccination (CDC)
Measles (CDC Measles (Rubeola))
Doctors’ talk measles (YouTube)
Measles (CDC: Measles Rubeola)
Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
Measles Vaccination: Know the Facts(ISDA: Infectious Diseases Society of America)
Deaths following vaccination: what does the evidence show (Vaccine)
Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
Weekly surveillance report: clift notes (CDC FluView)
Respiratory virus activity levels (CDC Respiratory Illnesses)
200 children die from flu (CIDRAP)
Weekly surveillance report: clift notes (CDC FluView)
FDA-CDC-DOD: 2025-2046 influenza vaccine composition (FDA)
RSV: Waste water scan for 11 pathogens (WastewaterSCan)
US respiratory virus activity (CDC Respiratory Illnesses)
RSV-Network (CDC Respiratory Syncytial virus Infection)
ACIP votes to expand recommendation for Pfizer’sRSV vaccine Abrysvo® to include adults aged 50 to 59 at increased risk of disease (Pfizer)
Respiratory syncytial virus and incidence of cardiovascular events: a nationwide self-controlled case series analysis (JACC Journals)
Waste water scan for 11 pathogens (WastewaterSCan)
COVID-19 deaths (CDC)
COVID-19 national and regional trends (CDC)
COVID-19 variant tracker (CDC)
SARS-CoV-2 genomes galore (Nextstrain)
Comorbidities associated with different degrees of severity in children and young people hospitalized with acute COVID-19 (Pediatric Infectious Disease Journal)
SHIELD-Utah study shows Novavax’s COVID-19 vaccine induces lower reactogenicity symptoms compared to mRNA (Novavax)
Interim clinical considerations for use of COVID-19 vaccines in the United States (CDC Vaccines & Immunizations)
Novavax says its COVID vaccine produces fewer, milder reactions than Pfizer version(CIDRAP)
US CDC advisers discuss narrower use of COVID-19 vaccines (Reuters)
Where to get pemgarda (Pemgarda)
EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)
Infusions center (Prime Fusions)
CDC Quarantine guidelines (CDC)
NIH COVID-19 treatment guidelines (NIH)
Drug interaction checker (University of Liverpool)
Infectious Disease Society guidelines for treatment and management (ID Society)
Molnupiravir safety and efficacy (JMV)
Convalescent plasma recommendation for immunocompromised (ID Society)
What to do when sick with a respiratory virus (CDC)
When your healthcare provider is infected/exposed with SARS-CoV-2 (CDC)
Managing healthcare staffing shortages (CDC)
Steroids, dexamethasone at the right time (OFID)
Anticoagulation guidelines (hematology.org)
Daniel Griffin’s evidence based medical practices for long COVID (OFID)
Long COVID hotline (Columbia : Columbia University Irving Medical Center)
The answers: Long COVID
Kidney Function following COVID-19 in children and adolescents(JAMA Network Open)
Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records(Nature Communications)
Great barrington declaration (gbdeclaration.org)
Clinical trials:
Effectiveness of transcranial direct current in patients with persistent COVID-19 with headaches and chronic pain.
Home-based Brain Stimulation Treatment for Post-acute Sequelae of COVID-19 (PASC)
Acupuncture for post COVID-19 Condition (Long COVID) neuropsychiatric symptoms
Pain relief with integrative medicine (prime)?: feasibility of acupuncture for long COVID
Electro-acupuncture for long COVID neuropsychiatric symptoms
Randomised study to investigate the effectiveness of acupuncture for the relief of long COIVD-19 related fatigue (ACU-COVID)
Vagus stimulation in female long COVID patients.(Vagus)
Stellate ganglion block with lidocaine for the treatment of COVID-19-induced parosmia (Stella)
Therapeutic updates on long COVID: Where things stand 5 years later (ID Society)
Reaching out to US house representative
Letters read on TWiV 1210
Dr. Griffin’s COVID treatment summary (pdf)
Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.